Drug Information

Drug General Information
Drug ID
DX2LJK
Drug Name
4-[2-(6-{[Bis-(4-fluoro-phenyl)-methyl]-carbamoyl}-benzofuran-2-yl)-phenoxy]-butyric acid
Synonyms
CHEMBL153258
Indication Discovery agent Investigative [1587926]
Formula
C32H25F2NO5
Canonical SMILES
OC(=O)CCCOc1ccccc1c2oc3cc(ccc3c2)C(=O)NC(c4ccc(F)cc4)c5ccc(F)cc5
InChI
InChI=1S/C32H25F2NO5/c33-24-13-9-20(10-14-24)31(21-11-15-25(34)16-12-21)35-32(38)23-8-7-22-18-29(40-28(22)19-23)26-4-1-2-5-27(26)39-17-3-6-30(36)37/h1-2,4-5,7-16,18-19,31H,3,6,17H2,(H,35,38)(H,36,37)
InChIKey
JUSOMMXOAWTGPZ-UHFFFAOYSA-N
Target and Pathway
Target(s) 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Target Info [1587926]
3-oxo-5-alpha-steroid 4-dehydrogenase 2 Target Info [1587926]
BioCyc Pathway Superpathway of steroid hormone biosynthesis
Allopregnanolone biosynthesis
Androgen biosynthesisPWY-7305:Superpathway of steroid hormone biosynthesis
Androgen biosynthesis
KEGG Pathway Steroid hormone biosynthesishsa00140:Steroid hormone biosynthesis
Prostate cancer
NetPath Pathway IL2 Signaling Pathway
PathWhiz Pathway Androgen and Estrogen Metabolism
Reactome Androgen biosynthesisR-HSA-193048:Androgen biosynthesis
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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