Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXR4LE
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| Drug Name |
4-[(R)-2-Cyano-2-((S)-2-phenylamino-3-m-tolyl-propionylamino)-ethoxymethyl]-benzoic acid
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| Synonyms |
CHEMBL133785
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H27N3O4
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| Canonical SMILES |
Cc1cccc(C[C@H](Nc2ccccc2)C(=O)N[C@@H](COCc3ccc(cc3)C(=O)O)C#N)c1
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| InChI |
InChI=1S/C27H27N3O4/c1-19-6-5-7-21(14-19)15-25(29-23-8-3-2-4-9-23)26(31)30-24(16-28)18-34-17-20-10-12-22(13-11-20)27(32)33/h2-14,24-25,29H,15,17-18H2,1H3,(H,30,31)(H,32,33)/t24-,25+/m1/s1
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| InChIKey |
CYMHTKKOUMCVCF-RPBOFIJWSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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