Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX8IWP
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| Drug Name |
4-(4-bromo-2-fluorophenoxy)-6,7-dimethoxyquinazoline
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| Synonyms |
CHEMBL1278149
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C16H12BrFN2O3
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| Canonical SMILES |
COc1cc2ncnc(Oc3ccc(Br)c(F)c3)c2cc1OC
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| InChI |
InChI=1S/C16H12BrFN2O3/c1-21-14-6-10-13(7-15(14)22-2)19-8-20-16(10)23-9-3-4-11(17)12(18)5-9/h3-8H,1-2H3
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| InChIKey |
DPDKUWBKXGAVEC-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Epidermal growth factor receptor III | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathway | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY network | |||||
| References | |||||
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