Drug Information

Drug General Information
Drug ID
DX1KEK
Drug Name
4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1-carboxylic acid 1-oxy-pyridin-3-yl ester
Synonyms
CHEMBL352727
Indication Discovery agent Investigative [1587926]
Formula
C24H22BrClN4O3
Canonical SMILES
[O-][n+]1cccc(OC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cc(Br)cnc35)c1
InChI
InChI=1S/C24H22BrClN4O3/c25-18-12-17-4-3-16-13-19(26)5-6-21(16)23(22(17)27-14-18)28-8-10-29(11-9-28)24(31)33-20-2-1-7-30(32)15-20/h1-2,5-7,12-15,23H,3-4,8-11H2
InChIKey
PZDLWSGRQNLKCH-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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