Drug Information

Drug General Information
Drug ID
DX8MDH
Drug Name
4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1,2-dicarboxylic acid 1-cyclohexylamide 2-[(3-imidazol-1-yl-propyl)-amide] 1-cyclopropylamide 2-[(pyridin-3-ylmethyl)-amide]
Synonyms
CHEMBL202381
Indication Discovery agent Investigative [1587926]
Formula
C29H30BrClN6O2
Canonical SMILES
Clc1ccc2C(N3CCN(C(C3)C(=O)NCc4cccnc4)C(=O)NC5CC5)c6ncc(Br)cc6CCc2c1
InChI
InChI=1S/C29H30BrClN6O2/c30-21-12-20-4-3-19-13-22(31)5-8-24(19)27(26(20)33-16-21)36-10-11-37(29(39)35-23-6-7-23)25(17-36)28(38)34-15-18-2-1-9-32-14-18/h1-2,5,8-9,12-14,16,23,25,27H,3-4,6-7,10-11,15,17H2,(H,34,38)(H,35,39)
InChIKey
VAIBMLXNEIEZII-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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