Drug Information

Drug General Information
Drug ID
DX8YVE
Drug Name
4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-2-[(pyridin-3-ylmethyl)-carbamoyl]-piperazine-1-carboxylic acid tert-butyl ester
Synonyms
CHEMBL201176
Indication Discovery agent Investigative [1587926]
Formula
C30H33BrClN5O3
Canonical SMILES
CC(C)(C)OC(=O)N1CCN(CC1C(=O)NCc2cccnc2)C3c4ccc(Cl)cc4CCc5cc(Br)cnc35
InChI
InChI=1S/C30H33BrClN5O3/c1-30(2,3)40-29(39)37-12-11-36(18-25(37)28(38)35-16-19-5-4-10-33-15-19)27-24-9-8-23(32)14-20(24)6-7-21-13-22(31)17-34-26(21)27/h4-5,8-10,13-15,17,25,27H,6-7,11-12,16,18H2,1-3H3,(H,35,38)
InChIKey
PKJPNZQYQXQHRH-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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