Drug Information

Drug General Information
Drug ID
DX7BDG
Drug Name
4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-(3-dimethylcarbamoyl-propionyl)-piperazine-2-carboxylic acid(pyridin-3-ylmethyl)-amide
Synonyms
CHEMBL382285
Indication Discovery agent Investigative [1587926]
Formula
C31H34BrClN6O3
Canonical SMILES
CN(C)C(=O)CCC(=O)N1CCN(CC1C(=O)NCc2cccnc2)C3c4ccc(Cl)cc4CCc5cc(Br)cnc35
InChI
InChI=1S/C31H34BrClN6O3/c1-37(2)27(40)9-10-28(41)39-13-12-38(19-26(39)31(42)36-17-20-4-3-11-34-16-20)30-25-8-7-24(33)15-21(25)5-6-22-14-23(32)18-35-29(22)30/h3-4,7-8,11,14-16,18,26,30H,5-6,9-10,12-13,17,19H2,1-2H3,(H,36,42)
InChIKey
WEYQMQWSOGQRDE-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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