Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX1ZXL
|
||||
| Drug Name |
3-isopropyl-N-(4-methyl-3-(3-(2-(methylamino)pyridin-4-yl)pyridin-2-yloxy)phenyl)benzamide
|
||||
| Synonyms |
CHEMBL245947
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H28N4O2
|
||||
| Canonical SMILES |
CNc1cc(ccn1)c2cccnc2Oc3cc(NC(=O)c4cccc(c4)C(C)C)ccc3C
|
||||
| InChI |
InChI=1S/C28H28N4O2/c1-18(2)20-7-5-8-22(15-20)27(33)32-23-11-10-19(3)25(17-23)34-28-24(9-6-13-31-28)21-12-14-30-26(16-21)29-4/h5-18H,1-4H3,(H,29,30)(H,32,33)
|
||||
| InChIKey |
VWYXMUBOMREMIL-UHFFFAOYSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.