Drug Information

Drug General Information
Drug ID
DX0EH3
Drug Name
3-(4-Chloro-phenyl)-2-[3-(4-methoxy-phenyl)-[1,2,4]oxadiazol-5-yl]-8-methyl-8-aza-bicyclo[3.2.1]octane
Synonyms
CHEMBL606996
Indication Discovery agent Investigative [1587926]
Formula
C23H24ClN3O2
Canonical SMILES
COc1ccc(cc1)c2noc(n2)C3C4CC[C@H](C[C@@H]3c5ccc(Cl)cc5)N4C
InChI
InChI=1S/C23H24ClN3O2/c1-27-17-9-12-20(27)21(19(13-17)14-3-7-16(24)8-4-14)23-25-22(26-29-23)15-5-10-18(28-2)11-6-15/h3-8,10-11,17,19-21H,9,12-13H2,1-2H3/t17-,19-,20?,21?/m1/s1
InChIKey
UHKLODIEZLNQLP-IDGBJLRDSA-N
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info [1587926]
Sodium-dependent serotonin transporter Target Info [1587926]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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