Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXVR5D
|
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| Drug Name |
3-(4-(3-phenyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-ylamino)phenyl)acrylic acid
|
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| Synonyms |
CHEMBL255735
|
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C19H14N6O2
|
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| Canonical SMILES |
OC(=O)\\C=C/c1ccc(Nc2ncc3nnn(c4ccccc4)c3n2)cc1
|
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| InChI |
InChI=1S/C19H14N6O2/c26-17(27)11-8-13-6-9-14(10-7-13)21-19-20-12-16-18(22-19)25(24-23-16)15-4-2-1-3-5-15/h1-12H,(H,26,27)(H,20,21,22)/b11-8-
|
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| InChIKey |
QEQDTPMQMKDYJW-FLIBITNWSA-N
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| Target and Pathway | |||||
| Target(s) | Aurora kinase A | Target Info | [1587926] | ||
| Glycogen synthase kinase-3 | Target Info | [1587926] | |||
| KEGG Pathway | Oocyte meiosis | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | Aurora B signaling | ||||
| Signaling by Aurora kinases | |||||
| Integrin-linked kinase signaling | |||||
| PLK1 signaling events | |||||
| Aurora A signalingbetacatenin_deg_pathway:Degradation of beta catenin | |||||
| Canonical Wnt signaling pathway | |||||
| FOXM1 transcription factor network | |||||
| Class I PI3K signaling events mediated by Akt | |||||
| References | |||||
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