Drug Information

Drug General Information
Drug ID
DX9PLO
Drug Name
2-Methyl-1-(8-methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct-2-yl)-propan-1-one
Synonyms
CHEMBL39589
Indication Discovery agent Investigative [1587926]
Formula
C22H27NO
Canonical SMILES
CC(C)C(=O)C1C2CCC(CC1c3ccc4ccccc4c3)N2C
InChI
InChI=1S/C22H27NO/c1-14(2)22(24)21-19(13-18-10-11-20(21)23(18)3)17-9-8-15-6-4-5-7-16(15)12-17/h4-9,12,14,18-21H,10-11,13H2,1-3H3
InChIKey
CPCMLFACLZPVQB-UHFFFAOYSA-N
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info [1587926]
Sodium-dependent serotonin transporter Target Info [1587926]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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