Drug Information

Drug General Information
Drug ID
DXJ7MW
Drug Name
2-Ethyl-10-piperazin-1-yl-4H-3-thia-4,9-diaza-benzo[f]azulene
Synonyms
CHEMBL368560
Indication Discovery agent Investigative [1587926]
Formula
C17H20N4S
Canonical SMILES
CCc1cc2C(=Nc3ccccc3Nc2s1)N4CCNCC4
InChI
InChI=1S/C17H20N4S/c1-2-12-11-13-16(21-9-7-18-8-10-21)19-14-5-3-4-6-15(14)20-17(13)22-12/h3-6,11,18,20H,2,7-10H2,1H3
InChIKey
DLBGDFORVMZNGR-UHFFFAOYSA-N
Target and Pathway
Target(s) Alpha-1 adrenergic receptor Target Info [1587926]
Histamine H1 receptor Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
PANTHER Pathway Histamine H1 receptor mediated signaling pathway
Reactome Histamine receptors
G alpha (q) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
IL-4 Signaling Pathway
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.