Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX0K5C
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| Drug Name |
2-Cyano-4-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrimidine-5-carboxylic acid (4-benzyl-1-methyl-piperidin-4-yl)-amide
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| Synonyms |
CHEMBL456135
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H36N6O
|
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| Canonical SMILES |
CN1CCC(Cc2ccccc2)(CC1)NC(=O)c3cnc(nc3NCC4CCC5(CC4)CC5)C#N
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| InChI |
InChI=1S/C28H36N6O/c1-34-15-13-28(14-16-34,17-21-5-3-2-4-6-21)33-26(35)23-20-30-24(18-29)32-25(23)31-19-22-7-9-27(10-8-22)11-12-27/h2-6,20,22H,7-17,19H2,1H3,(H,33,35)(H,30,31,32)
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| InChIKey |
NBEARLDWGIZSTM-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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