Drug Information

Drug General Information
Drug ID
DXI06X
Drug Name
2-(4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-oxo-ethyl}-piperidin-1-yl)-acetamide
Synonyms
CHEMBL92499
Indication Discovery agent Investigative [1587926]
Formula
C28H33Br2ClN4O2
Canonical SMILES
NC(=O)CN1CCC(CC(=O)N2CCC(CC2)[C@H]3c4ncc(Br)cc4CCc5cc(Cl)cc(Br)c35)CC1
InChI
InChI=1S/C28H33Br2ClN4O2/c29-21-12-20-2-1-19-13-22(31)14-23(30)26(19)27(28(20)33-15-21)18-5-9-35(10-6-18)25(37)11-17-3-7-34(8-4-17)16-24(32)36/h12-15,17-18,27H,1-11,16H2,(H2,32,36)/t27-/m1/s1
InChIKey
QDYHAAJQNSIFDZ-HHHXNRCGSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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