Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXB0HC
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| Drug Name |
2-(4-(3-phenyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-ylamino)phenoxy)acetic acid
|
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| Synonyms |
CHEMBL402541
|
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C18H14N6O3
|
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| Canonical SMILES |
OC(=O)COc1ccc(Nc2ncc3nnn(c4ccccc4)c3n2)cc1
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| InChI |
InChI=1S/C18H14N6O3/c25-16(26)11-27-14-8-6-12(7-9-14)20-18-19-10-15-17(21-18)24(23-22-15)13-4-2-1-3-5-13/h1-10H,11H2,(H,25,26)(H,19,20,21)
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| InChIKey |
DNCXPYGCTRGWJY-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Aurora kinase A | Target Info | [1587926] | ||
| Glycogen synthase kinase-3 | Target Info | [1587926] | |||
| KEGG Pathway | Oocyte meiosis | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | Aurora B signaling | ||||
| Signaling by Aurora kinases | |||||
| Integrin-linked kinase signaling | |||||
| PLK1 signaling events | |||||
| Aurora A signalingbetacatenin_deg_pathway:Degradation of beta catenin | |||||
| Canonical Wnt signaling pathway | |||||
| FOXM1 transcription factor network | |||||
| Class I PI3K signaling events mediated by Akt | |||||
| References | |||||
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