Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX9PQM
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| Drug Name |
1H-Indole-2-carboxylic acid {(S)-1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-amide
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| Synonyms |
CHEMBL304918
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H30N4O3
|
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| Canonical SMILES |
COc1ccc(NCCNC(=O)[C@H](CC(C)C)NC(=O)c2cc3ccccc3[nH]2)cc1
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| InChI |
InChI=1S/C24H30N4O3/c1-16(2)14-21(28-24(30)22-15-17-6-4-5-7-20(17)27-22)23(29)26-13-12-25-18-8-10-19(31-3)11-9-18/h4-11,15-16,21,25,27H,12-14H2,1-3H3,(H,26,29)(H,28,30)/t21-/m0/s1
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| InChIKey |
SRYPGDMXSHZMAX-NRFANRHFSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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