| Drug General Information |
| Drug ID |
DX8HGA
|
| Drug Name |
1-Chloro-6-(4-hydroxy-2-methyl-phenyl)-naphthalen-2-ol
|
| Synonyms |
CHEMBL191300
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Formula |
C17H13ClO2
|
| Canonical SMILES |
Cc1cc(O)ccc1c2ccc3c(Cl)c(O)ccc3c2
|
| InChI |
InChI=1S/C17H13ClO2/c1-10-8-13(19)4-6-14(10)11-2-5-15-12(9-11)3-7-16(20)17(15)18/h2-9,19-20H,1H3
|
| InChIKey |
GGWIHGXEDCXOIL-UHFFFAOYSA-N
|
| Target and Pathway |
| Target(s) |
Estrogen receptor beta |
Target Info |
|
[1]
|
|---|
| Estrogen receptor |
Target Info |
|
[1]
|
|
KEGG Pathway
|
Estrogen signaling pathway
|
|
Prolactin signaling pathwayhsa04915:Estrogen signaling pathway
|
|
Prolactin signaling pathway
|
|
Thyroid hormone signaling pathway
|
|
Endocrine and other factor-regulated calcium reabsorption
|
|
Proteoglycans in cancer
|
|
NetPath Pathway
|
FSH Signaling Pathway
|
|
EGFR1 Signaling Pathway
|
|
RANKL Signaling Pathway
|
|
Pathway Interaction Database
|
Plasma membrane estrogen receptor signaling
|
|
Validated nuclear estrogen receptor beta network
|
|
Validated nuclear estrogen receptor alpha networksmad2_3nuclearpathway:Regulation of nuclear SMAD2/3 signaling
|
|
Signaling events mediated by HDAC Class II
|
|
LKB1 signaling events
|
|
Regulation of Telomerase
|
|
ATF-2 transcription factor network
|
|
AP-1 transcription factor network
|
|
FOXM1 transcription factor network
|
|
Validated nuclear estrogen receptor alpha network
|
|
Signaling mediated by p38-alpha and p38-beta
|
|
FOXA1 transcription factor network
|
|
Reactome
|
Nuclear Receptor transcription pathwayR-HSA-1251985:Nuclear signaling by ERBB4
|
|
Nuclear Receptor transcription pathway
|
|
WikiPathways
|
SIDS Susceptibility Pathways
|
|
Ovarian Infertility Genes
|
|
Integrated Pancreatic Cancer Pathway
|
|
Nuclear ReceptorsWP712:Estrogen signaling pathway
|
|
Nuclear Receptors Meta-Pathway
|
|
Estrogen Receptor Pathway
|
|
Signaling by ERBB4
|
|
JAK/STAT
|
|
Leptin signaling pathway
|
|
miR-targeted genes in muscle cell - TarBase
|
|
Integrated Breast Cancer Pathway
|
|
Nuclear Receptors
|
| References |
| REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 |
|---|
