Drug Information
| Drug General Information | |||||
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| Drug ID |
DXR9HZ
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| Drug Name |
19-methyl-3-(2-methylpropyl)-7-[(1E)-1-[(propan-2-yloxy)imino]ethyl]-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one
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| Synonyms |
CHEMBL403823
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C29H33N5O2
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| Canonical SMILES |
CC(C)Cn1c2ccc(cc2c3c4CNC(=O)c4c5c(CCc6nn(C)cc56)c13)\\C(=N\\OC(C)C)\\C
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| InChI |
InChI=1S/C29H33N5O2/c1-15(2)13-34-24-10-7-18(17(5)32-36-16(3)4)11-20(24)26-21-12-30-29(35)27(21)25-19(28(26)34)8-9-23-22(25)14-33(6)31-23/h7,10-11,14-16H,8-9,12-13H2,1-6H3,(H,30,35)/b32-17+
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| InChIKey |
BZALTIILUKKHEU-VTNSRFBWSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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