Drug Information

Drug General Information
Drug ID
DX5A1W
Drug Name
17-benzyl-15,18-dioxo-(17R)-2-oxa-9,11,16,19-tetraazapentacyclo[18.6.2.13,7.09,13.024,28]nonacosa-1(27),3,5,7(29),10,12,20(28),21,23,25-decaen-4-yl cyanide
Synonyms
CHEMBL52610
Indication Discovery agent Investigative [1587926]
Formula
C32H25N5O3
Canonical SMILES
O=C1Cc2cncn2Cc3ccc(C#N)c(Oc4ccc5cccc(NC(=O)[C@@H](Cc6ccccc6)N1)c5c4)c3
InChI
InChI=1S/C32H25N5O3/c33-17-24-10-9-22-14-30(24)40-26-12-11-23-7-4-8-28(27(23)16-26)36-32(39)29(13-21-5-2-1-3-6-21)35-31(38)15-25-18-34-20-37(25)19-22/h1-12,14,16,18,20,29H,13,15,19H2,(H,35,38)(H,36,39)/t29-/m1/s1
InChIKey
QGCNWBQUPNGUPL-GDLZYMKVSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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