Drug Information
| Drug General Information | |||||
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| Drug ID |
DXN43W
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| Drug Name |
15,16-dimethyl-17-oxo-(16R)-2-oxa-9,11,15,18-tetraazapentacyclo[17.6.2.13,7.09,13.023,27]octacosa-1(26),3,5,7(28),10,12,19(27),20,22,24-decaen-4-yl cyanide
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| Synonyms |
CHEMBL54969
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| Indication | Discovery agent | Investigative | [1] | ||
| Formula |
C26H23N5O2
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| Canonical SMILES |
C[C@H]1N(C)Cc2cncn2Cc3ccc(C#N)c(Oc4ccc5cccc(NC1=O)c5c4)c3
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| InChI |
InChI=1S/C26H23N5O2/c1-17-26(32)29-24-5-3-4-19-8-9-22(11-23(19)24)33-25-10-18(6-7-20(25)12-27)14-31-16-28-13-21(31)15-30(17)2/h3-11,13,16-17H,14-15H2,1-2H3,(H,29,32)/t17-/m1/s1
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| InChIKey |
BAQAZCQBLRUMRU-QGZVFWFLSA-N
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| Target and Pathway | |||||
| Target(s) | Farnesyltransferase | Target Info | [1] | ||
| Protein farnesyltransferase beta subunit | Target Info | [1] | |||
| KEGG Pathway | Terpenoid backbone biosynthesis | ||||
| Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis | |||||
| Biosynthesis of antibiotics | |||||
| NetPath Pathway | TSH Signaling Pathway | ||||
| Reactome | Apoptotic cleavage of cellular proteins | ||||
| Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade | |||||
| WikiPathways | Visual phototransduction | ||||
| Apoptotic execution phaseWP2776:Visual phototransduction | |||||
| References | |||||
| REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 | ||||
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