Drug Information

Drug General Information
Drug ID
DXN43W
Drug Name
15,16-dimethyl-17-oxo-(16R)-2-oxa-9,11,15,18-tetraazapentacyclo[17.6.2.13,7.09,13.023,27]octacosa-1(26),3,5,7(28),10,12,19(27),20,22,24-decaen-4-yl cyanide
Synonyms
CHEMBL54969
Indication Discovery agent Investigative [1587926]
Formula
C26H23N5O2
Canonical SMILES
C[C@H]1N(C)Cc2cncn2Cc3ccc(C#N)c(Oc4ccc5cccc(NC1=O)c5c4)c3
InChI
InChI=1S/C26H23N5O2/c1-17-26(32)29-24-5-3-4-19-8-9-22(11-23(19)24)33-25-10-18(6-7-20(25)12-27)14-31-16-28-13-21(31)15-30(17)2/h3-11,13,16-17H,14-15H2,1-2H3,(H,29,32)/t17-/m1/s1
InChIKey
BAQAZCQBLRUMRU-QGZVFWFLSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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