Drug Information

Drug General Information
Drug ID
DXTQ6E
Drug Name
1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-pyridin-3-yl-propan-1-one
Synonyms
CHEMBL355879
Indication Discovery agent Investigative [1587926]
Formula
C26H27ClN4O
Canonical SMILES
CC(C(=O)N1CCN(CC1)C2c3ccc(Cl)cc3CCc4cccnc24)c5cccnc5
InChI
InChI=1S/C26H27ClN4O/c1-18(21-5-2-10-28-17-21)26(32)31-14-12-30(13-15-31)25-23-9-8-22(27)16-20(23)7-6-19-4-3-11-29-24(19)25/h2-5,8-11,16-18,25H,6-7,12-15H2,1H3
InChIKey
LHCCKAKNHQFTRO-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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