Drug Information

Drug General Information
Drug ID
DXI0TF
Drug Name
1-[4-(8-Chloro-3-methyl-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-pyridin-3-yl-ethanone
Synonyms
CHEMBL337193
Indication Discovery agent Investigative [1587926]
Formula
C27H26ClN3O
Canonical SMILES
Cc1cnc2C(=C3CCN(CC3)C(=O)Cc4cccnc4)c5ccc(Cl)cc5CCc2c1
InChI
InChI=1S/C27H26ClN3O/c1-18-13-22-5-4-21-15-23(28)6-7-24(21)26(27(22)30-16-18)20-8-11-31(12-9-20)25(32)14-19-3-2-10-29-17-19/h2-3,6-7,10,13,15-17H,4-5,8-9,11-12,14H2,1H3
InChIKey
MGWLKIQUEZCJEU-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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