Drug Information

Drug General Information
Drug ID
DXR3K6
Drug Name
1-[4-(8-Chloro-10-methyl-10,11-dihydro-5H-4,10-diaza-dibenzo[a,d]cyclohepten-5-yl)-piperazin-1-yl]-2-(1-oxy-pyridin-4-yl)-ethanone
Synonyms
CHEMBL84036
Indication Discovery agent Investigative [1587926]
Formula
C25H26ClN5O2
Canonical SMILES
CN1Cc2cccnc2C(N3CCN(CC3)C(=O)Cc4cc[n+]([O-])cc4)c5ccc(Cl)cc15
InChI
InChI=1S/C25H26ClN5O2/c1-28-17-19-3-2-8-27-24(19)25(21-5-4-20(26)16-22(21)28)30-13-11-29(12-14-30)23(32)15-18-6-9-31(33)10-7-18/h2-10,16,25H,11-15,17H2,1H3
InChIKey
LQKAVYVOISWFQF-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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