Drug Information

Drug General Information
Drug ID
DX2TFK
Drug Name
1-[4-(3,5-Dibromo-8-chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-(1-oxy-pyridin-4-yl)-ethanone
Synonyms
CHEMBL416231
Indication Discovery agent Investigative [1587926]
Formula
C26H22Br2ClN3O2
Canonical SMILES
[O-][n+]1ccc(CC(=O)N2CCC(CC2)C3c4ccc(Cl)cc4C=C(Br)c5cc(Br)cnc35)cc1
InChI
InChI=1S/C26H22Br2ClN3O2/c27-19-14-22-23(28)13-18-12-20(29)1-2-21(18)25(26(22)30-15-19)17-5-7-31(8-6-17)24(33)11-16-3-9-32(34)10-4-16/h1-4,9-10,12-15,17,25H,5-8,11H2
InChIKey
GJOYCZXIAXQQNR-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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