Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX3UKW
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| Drug Name |
1-(4-(4-amino-6-benzylthieno[2,3-d]pyrimidin-5-yl)phenyl)-3-m-tolylurea
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| Synonyms |
CHEMBL372755
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H23N5OS
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| Canonical SMILES |
Cc1cccc(NC(=O)Nc2ccc(cc2)c3c(Cc4ccccc4)sc5ncnc(N)c35)c1
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| InChI |
InChI=1S/C27H23N5OS/c1-17-6-5-9-21(14-17)32-27(33)31-20-12-10-19(11-13-20)23-22(15-18-7-3-2-4-8-18)34-26-24(23)25(28)29-16-30-26/h2-14,16H,15H2,1H3,(H2,28,29,30)(H2,31,32,33)
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| InChIKey |
UKVIWMOPJDEZMM-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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