Drug Information

Drug General Information
Drug ID
DXW2NH
Drug Name
1-(2-{4-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one
Synonyms
CHEMBL431786
Indication Discovery agent Investigative [1587926]
Formula
C24H28F2N4O
Canonical SMILES
Fc1ccc(cc1)C2CC(N3CCN(CCN4CCNC4=O)CC3)c5cc(F)ccc25
InChI
InChI=1S/C24H28F2N4O/c25-18-3-1-17(2-4-18)21-16-23(22-15-19(26)5-6-20(21)22)29-12-9-28(10-13-29)11-14-30-8-7-27-24(30)31/h1-6,15,21,23H,7-14,16H2,(H,27,31)
InChIKey
MYVPKBWFYFYMBK-UHFFFAOYSA-N
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info [1587926]
Sodium-dependent serotonin transporter Target Info [1587926]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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