Drug Information
| Drug General Information | |||||
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| Drug ID |
DXHE4A
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| Drug Name |
[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-quinolin-8-yl-methanone
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| Synonyms |
CHEMBL355262
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| Indication | Discovery agent | Investigative | [1] | ||
| Formula |
C28H24BrClN4O
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| Canonical SMILES |
Clc1ccc2C(N3CCN(CC3)C(=O)c4cccc5cccnc45)c6ncc(Br)cc6CCc2c1
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| InChI |
InChI=1S/C28H24BrClN4O/c29-21-15-20-7-6-19-16-22(30)8-9-23(19)27(26(20)32-17-21)33-11-13-34(14-12-33)28(35)24-5-1-3-18-4-2-10-31-25(18)24/h1-5,8-10,15-17,27H,6-7,11-14H2
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| InChIKey |
GCTRGRVRBMORMC-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Farnesyltransferase | Target Info | [1] | ||
| Protein farnesyltransferase beta subunit | Target Info | [1] | |||
| KEGG Pathway | Terpenoid backbone biosynthesis | ||||
| Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis | |||||
| Biosynthesis of antibiotics | |||||
| NetPath Pathway | TSH Signaling Pathway | ||||
| Reactome | Apoptotic cleavage of cellular proteins | ||||
| Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade | |||||
| WikiPathways | Visual phototransduction | ||||
| Apoptotic execution phaseWP2776:Visual phototransduction | |||||
| References | |||||
| REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 | ||||
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