Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX1WGI
|
||||
| Drug Name |
[1-(3-tert-Butylsulfanyl-2-oxo-1-phenethyl-propylcarbamoyl)-3-methyl-butyl]-carbamic acid pyridin-3-ylmethyl ester
|
||||
| Synonyms |
CHEMBL352168
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H39N3O4S
|
||||
| Canonical SMILES |
CC(C)C[C@H](NC(=O)OCc1cccnc1)C(=O)N[C@@H](CCc2ccccc2)C(=O)CSC(C)(C)C
|
||||
| InChI |
InChI=1S/C28H39N3O4S/c1-20(2)16-24(31-27(34)35-18-22-12-9-15-29-17-22)26(33)30-23(25(32)19-36-28(3,4)5)14-13-21-10-7-6-8-11-21/h6-12,15,17,20,23-24H,13-14,16,18-19H2,1-5H3,(H,30,33)(H,31,34)/t23-,24-/m0/s1
|
||||
| InChIKey |
WUKLOIZMYLWBNL-ZEQRLZLVSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.