Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXPZ7Y
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| Drug Name |
[1-(1-Benzyl-3-tert-butylsulfanyl-2-oxo-propylcarbamoyl)-3-methyl-butyl]-carbamic acid pyridin-4-ylmethyl ester
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| Synonyms |
CHEMBL436227
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H37N3O4S
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| Canonical SMILES |
CC(C)C[C@H](NC(=O)OCc1ccncc1)C(=O)N[C@@H](Cc2ccccc2)C(=O)CSC(C)(C)C
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| InChI |
InChI=1S/C27H37N3O4S/c1-19(2)15-23(30-26(33)34-17-21-11-13-28-14-12-21)25(32)29-22(16-20-9-7-6-8-10-20)24(31)18-35-27(3,4)5/h6-14,19,22-23H,15-18H2,1-5H3,(H,29,32)(H,30,33)/t22-,23-/m0/s1
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| InChIKey |
JIMHQYPASLNACB-GOTSBHOMSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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