Drug Information

Drug General Information
Drug ID
DX8DQG
Drug Name
(S)-2-((4E,8E)-2-{[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-amino}-5,9,13-trimethyl-tetradeca-4,8,12-trienoylamino)-3-phenyl-propionic acid
Synonyms
CHEMBL285550
Indication Discovery agent Investigative [1587926]
Formula
C38H47N5O3
Canonical SMILES
CC(=CCC\\C(=C\\CC\\C(=C\\CC(NCc1cncn1Cc2ccc(cc2)C#N)C(=O)N[C@@H](Cc3ccccc3)C(=O)O)\\C)\\C)C
InChI
InChI=1S/C38H47N5O3/c1-28(2)10-8-11-29(3)12-9-13-30(4)16-21-35(37(44)42-36(38(45)46)22-31-14-6-5-7-15-31)41-25-34-24-40-27-43(34)26-33-19-17-32(23-39)18-20-33/h5-7,10,12,14-20,24,27,35-36,41H,8-9,11,13,21-22,25-26H2,1-4H3,(H,42,44)(H,45,46)/b29-12+,30-16+/t35?,36-/m0/s1
InChIKey
LVJWJCSHBVDKJR-LLHYOLDNSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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