Drug Information

Drug General Information
Drug ID
DXVO2F
Drug Name
(R)-5-(4-Methoxy-benzenesulfonyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid hydroxyamide
Synonyms
CHEMBL337793
Indication Discovery agent Investigative [1587926]
Formula
C14H16N4O5S
Canonical SMILES
COc1ccc(cc1)S(=O)(=O)N2Cc3[nH]cnc3C[C@@H]2C(=O)NO
InChI
InChI=1S/C14H16N4O5S/c1-23-9-2-4-10(5-3-9)24(21,22)18-7-12-11(15-8-16-12)6-13(18)14(19)17-20/h2-5,8,13,20H,6-7H2,1H3,(H,15,16)(H,17,19)/t13-/m1/s1
InChIKey
UNRFEBNSHUZKHJ-CYBMUJFWSA-N
Target and Pathway
Target(s) Stromelysin-1 Target Info [1587926]
Neutrophil collagenase Target Info [1587926]
KEGG Pathway TNF signaling pathway
Transcriptional misregulation in cancer
Rheumatoid arthritis
NetPath Pathway IL1 Signaling Pathway
IL4 Signaling Pathway
PANTHER Pathway Plasminogen activating cascade
CCKR signaling map STP00004:Alzheimer disease-presenilin pathway
Pathway Interaction Database Posttranslational regulation of adherens junction stability and dissassembly
p75(NTR)-mediated signaling
Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome Collagen degradation
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Assembly of collagen fibrils and other multimeric structures
EGFR Transactivation by GastrinR-HSA-1442490:Collagen degradation
WikiPathways Activation of Matrix Metalloproteinases
Gastrin-CREB signalling pathway via PKC and MAPK
Oncostatin M Signaling Pathway
Matrix MetalloproteinasesWP2769:Activation of Matrix Metalloproteinases
Matrix Metalloproteinases
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.