Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX1LKV
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| Drug Name |
(R)-4-methyl-2-[3'-(2-piperazin-1-ylmethyl-thiazol-4-yl)-biphenyl-3-yl]-pentanoic acid cyanomethyl-amide
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| Synonyms |
CHEMBL213194
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H33N5OS
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| Canonical SMILES |
CC(C)C[C@@H](C(=O)NCC#N)c1cccc(c1)c2cccc(c2)c3csc(CN4CCNCC4)n3
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| InChI |
InChI=1S/C28H33N5OS/c1-20(2)15-25(28(34)31-10-9-29)23-7-3-5-21(16-23)22-6-4-8-24(17-22)26-19-35-27(32-26)18-33-13-11-30-12-14-33/h3-8,16-17,19-20,25,30H,10-15,18H2,1-2H3,(H,31,34)/t25-/m1/s1
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| InChIKey |
GGQXMEFMGFPZJK-RUZDIDTESA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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