Drug Information

Drug General Information
Drug ID
DXW0TT
Drug Name
(R)-2-Amino-1-[4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-3-mercapto-propan-1-one
Synonyms
CHEMBL170436
Indication Discovery agent Investigative [1587926]
Formula
C21H24BrClN4OS
Canonical SMILES
N[C@@H](CS)C(=O)N1CCN(CC1)C2c3ccc(Cl)cc3CCc4cc(Br)cnc24
InChI
InChI=1S/C21H24BrClN4OS/c22-15-9-14-2-1-13-10-16(23)3-4-17(13)20(19(14)25-11-15)26-5-7-27(8-6-26)21(28)18(24)12-29/h3-4,9-11,18,20,29H,1-2,5-8,12,24H2/t18-,20?/m0/s1
InChIKey
UHVULAGTUOXSEX-LROBGIAVSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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