Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXM1D9
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| Drug Name |
(E/Z)-4-(2-(1-benzyl-4-phenyl-1H-imidazol-5-yl)vinyl)pyrimidin-2-amine
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| Synonyms |
CHEMBL499891
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C22H19N5
|
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| Canonical SMILES |
Nc1nccc(\\C=C\\c2c(ncn2Cc3ccccc3)c4ccccc4)n1
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| InChI |
InChI=1S/C22H19N5/c23-22-24-14-13-19(26-22)11-12-20-21(18-9-5-2-6-10-18)25-16-27(20)15-17-7-3-1-4-8-17/h1-14,16H,15H2,(H2,23,24,26)/b12-11+
|
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| InChIKey |
VHTDDEQGXAKILP-VAWYXSNFSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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