Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXY8SF
|
||||
| Drug Name |
(1S,2R,3R)-1-(7-Fluoro-1,2,3,4-tetrahydropyrido[3'4':3,4]pyrazolo[1,5-a]pyridine-2-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylic acid
|
||||
| Synonyms |
CHEMBL1767011
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C21H21FN4O4S
|
||||
| Canonical SMILES |
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N3CCc4c(C3)nn5cc(F)ccc45)C(=O)O
|
||||
| InChI |
InChI=1S/C21H21FN4O4S/c1-13-19(14-5-3-2-4-6-14)21(13,20(27)28)24-31(29,30)25-10-9-16-17(12-25)23-26-11-15(22)7-8-18(16)26/h2-8,11,13,19,24H,9-10,12H2,1H3,(H,27,28)/t13-,19-,21+/m1/s1
|
||||
| InChIKey |
KIMAXDZENSBFAC-DYHNYNMBSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Interstitial collagenase | Target Info | [1587926] | ||
| Matrix metalloproteinase-14 | Target Info | [1587926] | |||
| Pathway Interaction Database | Endothelins | ||||
| Validated transcriptional targets of AP1 family members Fra1 and Fra2 | |||||
| Glucocorticoid receptor regulatory network | |||||
| AP-1 transcription factor network | |||||
| Syndecan-1-mediated signaling eventshif2pathway:HIF-2-alpha transcription factor network | |||||
| Signaling events mediated by focal adhesion kinase | |||||
| WikiPathways | TGF beta Signaling Pathway | ||||
| Bladder Cancer | |||||
| Activation of Matrix Metalloproteinases | |||||
| Degradation of collagen | |||||
| Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | |||||
| Oncostatin M Signaling Pathway | |||||
| Prostate Cancer | |||||
| Integrated Breast Cancer Pathway | |||||
| Integrated Cancer pathway | |||||
| Cell surface interactions at the vascular wall | |||||
| Matrix MetalloproteinasesWP615:Senescence and Autophagy in Cancer | |||||
| AGE/RAGE pathway | |||||
| Matrix Metalloproteinases | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.