Target Information

Target General Infomation
Target ID
T00417
Target Name
GABA(B) receptor
Target Type
Successful
Disease Anesthesia narcolepsy [ICD9: 338, 347; ICD10: G47.4, R20.0]
Multiple scierosis [ICD9: 340; ICD10: G35]
Drugs and Mode of Action
Drug(s) Baclofen Drug Info Approved Multiple scierosis [536096], [538665]
Gamma Hydroxybutyric Acid Drug Info Approved Anesthesia narcolepsy [467952], [536382]
Modulator Baclofen Drug Info [556264]
Gamma Hydroxybutyric Acid Drug Info [556264]
References
Ref 467952(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4711).
Ref 536096Development of medications for alcohol use disorders: recent advances and ongoing challenges. Expert Opin Emerg Drugs. 2005 May;10(2):323-43.
Ref 536382Sodium oxybate: a review of its use in the management of narcolepsy. CNS Drugs. 2007;21(4):337-54.
Ref 538665(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1084).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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