Target Information
| Target General Infomation | |||||
|---|---|---|---|---|---|
| Target ID |
T37271
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| Former ID |
TTDR00415
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| Target Name |
Lactosylceramide alpha-2,3-sialyltransferase
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| Gene Name |
ST3GAL5
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| Synonyms |
CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; Ganglioside GM3 synthase; ST3Gal V; Sialyltransferase 9; UNQ2510/PRO5998; ST3GAL5
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| Target Type |
Research
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| Function |
Catalyzes the formation of ganglioside GM3 (alpha-N- acetylneuraminyl-2,3-beta-D-galactosyl-1, 4-beta-D- glucosylceramide).
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| BioChemical Class |
Transferases of glycosyl groups
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| UniProt ID | |||||
| EC Number |
EC 2.4.99.9
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| Sequence |
MRTKAAGCAERRPLQPRTEAAAAPAGRAMPSEYTYVKLRSDCSRPSLQWYTRAQSKMRRP
SLLLKDILKCTLLVFGVWILYILKLNYTTEECDMKKMHYVDPDHVKRAQKYAQQVLQKEC RPKFAKTSMALLFEHRYSVDLLPFVQKAPKDSEAESKYDPPFGFRKFSSKVQTLLELLPE HDLPEHLKAKTCRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPVEGYSEHVGNKTTI RMTYPEGAPLSDLEYYSNDLFVAVLFKSVDFNWLQAMVKKETLPFWVRLFFWKQVAEKIP LQPKHFRILNPVIIKETAFDILQYSEPQSRFWGRDKNVPTIGVIAVVLATHLCDEVSLAG FGYDLNQPRTPLHYFDSQCMAAMNFQTMHNVTTETKFLLKLVKEGVVKDLSGGIDREF |
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| Pathways | |||||
| KEGG Pathway | Glycosphingolipid biosynthesis - ganglio series | ||||
| Metabolic pathways | |||||
| Reactome | Sialic acid metabolism | ||||
| WikiPathways | Ganglio Sphingolipid Metabolism | ||||
| References | |||||
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