Target Information

Target General Infomation
Target ID
T99665
Former ID
TTDI03210
Target Name
GABAA receptor rho1 subunit
Gene Name
GABRR1
Synonyms
GABRR1
Target Type
Research
UniProt ID
P24046
Sequence
MLAVPNMRFGIFLLWWGWVLATESRMHWPGREVHEMSKKGRPQRQRREVHEDAHKQVSPI
LRRSPDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTM
TLYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRV
QPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTD
ERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSW
VSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVL
EYAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKP
DRMMVQLTLASERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYWSIFS
Agonist (+/-)-cis-2-CAMP Drug Info [543820]
5-Me-IAA Drug Info [543820]
CACA Drug Info [534007]
Antagonist aza-THIP Drug Info [543820]
cis-3-ACPBPA Drug Info [543820]
isonipecotic acid Drug Info [543820]
piperidine-4-sulphonic acid Drug Info [543820]
TPMPA Drug Info [543820]
trans-3-ACPBPA Drug Info [543820]
Blocker (channel blocker) TBPS Drug Info [543820]
References
Ref 534007Characterization of bicuculline/baclofen-insensitive (rho-like) gamma-aminobutyric acid receptors expressed in Xenopus oocytes. II. Pharmacology of gamma-aminobutyric acidA and gamma-aminobutyric acidB receptor agonists and antagonists. Mol Pharmacol. 1993 Apr;43(4):609-25.
Ref 543820(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 420).

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