Target General Infomation
Target ID
T66350
Former ID
TTDR00036
Target Name
Ras-related protein Rab-9A
Gene Name
RAB9A
Synonyms
RAB9A
Target Type
Successful
Disease Fungal infections [ICD9: 110-118; ICD10: B35-B49]
Function
Involved in the transport of proteins between the endosomes and the trans Golgi network.
BioChemical Class
Small GTPase superfamily
UniProt ID
Sequence
MAGKSSLFKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVDGHFVTMQI
WDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFV
ILGNKIDISERQVSTEEAQAWCRDNGDYPYFETSAKDATNVAAAFEEAVRRVLATEDRSD
HLIQTDTVNLHRKPKPSSSCC
Drugs and Mode of Action
Drug(s) Benzoic Acid Drug Info Approved Fungal infections [467802], [551871]
Inhibitor Benzoic Acid Drug Info [551393]
Guanosine-5'-Diphosphate Drug Info [551393]
Pathways
KEGG Pathway Measles
References
Ref 467802(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4565).
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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