Resistance mutation info of target
Target General Information | |||||
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Target ID | T67619 | ||||
Target Name | RAC-alpha serine/threonine-protein kinase (AKT1) | Target Info | |||
Gene Name | AKT1 | ||||
Species | Homo sapiens | ||||
Uniprot ID | AKT1_HUMAN | ||||
Sequence | MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQC QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDF RSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL ILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKK LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA [Homo sapiens] |
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Drug Resistance Mutation and Corresponding Drugs | |||||
Mutation Info | Missense: E17K | ||||
Mutation Info | Missense: Q79K |
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