Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| MMP2 --- MMP9 | 3-[(S)-2-(4-Methoxy-phenyl)-1-methylcarbamoyl-ethylsulfamoyl]-5-phenyl-pentanoic acid | Drug Info |
| MMP2 --- MMP9 | 4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(4'-isopropyl-biphenyl-4-sulfonyl)-butyric acid | Drug Info |
| MMP2 --- MMP9 | N-Hydroxy-2-{4-[5-(4-methoxy-phenyl)-oxazol-2-yl]-benzenesulfonylamino}-3-methyl-butyramide | Drug Info |
| MMP2 --- MMP9 | 5-(4-Phenoxyphenyl)-5-(4-(3-(N-(5-methylisoxazol-3-yl)sulfamoyl)benzoyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| MMP2 --- MMP9 | 11-(2',6'-Difluoro-biphenyl-4-ylmethyl)-2,10-dioxo-1-oxa-3,9-diaza-cyclopentadecane-8,12-dicarboxylic acid 12-hydroxyamide 8-[(2-morpholin-4-yl-2-oxo-ethyl)-amide] | Drug Info |
| MMP2 --- MMP9 | 5-(4-Phenoxyphenyl)-5-(4-((8-(dimethylamino)napththalen-4-yl)sulfonyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| MMP2 --- MMP9 | (R)-2-[5-(4-Butoxy-phenylethynyl)-thiophene-2-sulfonylamino]-3-(1H-indol-3-yl)-propionic acid | Drug Info |
| MMP2 --- MMP9 | N-Hydroxy-2-{3-methyl-3-[4-(4-nitro-benzyloxy)-phenyl]-2-oxo-pyrrolidin-1-yl}-propionamide | Drug Info |
| MMP2 --- MMP9 | (S)-2-Amino-N-hydroxy-2-{(R)-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-acetamide | Drug Info |
| MMP2 --- MMP9 | (3R,4S)-3-Hydroxycarbamoyl-4-[4-(2-methyl-quinolin-4-ylmethoxy)-phenylcarbamoyl]-piperidine-1-carboxylic acid methyl ester | Drug Info |
| MMP2 --- MMP9 | (-)-(R)-N-(1-hydroxy-2-oxo-2,3,4,7-tetrahydro-1H-azepin-3-yl)-4-(pyridin-2-yloxy)benzenesulfonamide | Drug Info |
| MMP2 --- MMP9 | {5-[7-(3,5-Dimethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-5-hydroxycarbamoyl-pentyl}-carbamic acid tert-butyl ester | Drug Info |
| MMP2 --- MMP9 | 1-((4-(4-chlorophenoxy)phenylsulfonyl)methyl)-3-hydroxypyridin-2(1H)-one | Drug Info |
| MMP2 --- MMP9 | N-Hydroxy-N-{1-(1-methyl-1H-indol-2-yl)-2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-ethyl}-formamide | Drug Info |
| MMP2 --- MMP9 | (S)-N-hydroxy-2-(piperidin-1-yl)-3-(N-(4-(4-(trifluoromethyl)phenoxy)phenyl)methan-2-ylsulfonamido)propanamide | Drug Info |
| MMP2 --- MMP9 | 4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-[4-(3-methoxy-phenylethynyl)-phenylsulfanyl]-butyric acid | Drug Info |
| MMP2 --- MMP9 | 2-{4-[5-(4-Methoxy-phenyl)-thiazol-2-yl]-benzenesulfonylamino}-3-methyl-butyric acid | Drug Info |
| MMP2 --- MMP9 | (S)-N,2-dihydroxy-3-(N-(4-(4-(trifluoromethyl)phenoxy)phenyl)methan-15-ylsulfonamido)propanamide | Drug Info |
| MMP2 --- MMP9 | (R)-4-(4-chlorophenoxy)-N-(1-hydroxy-2-oxo-2,3,4,7-tetrahydro-1H-azepin-3-yl)-N-(2-(4-methylpiperazin-1-yl)ethyl)benzenesulfonamide | Drug Info |
| MMP2 --- MMP9 | (6S,7S)-6-[4-(3-methoxy-phenyl)-3,6-dihydro-2H-pyridine-1-carbonyl]-5-aza-spiro[2.5]octane-7-carboxylic acid hydroxyamide | Drug Info |
| MMP2 --- MMP9 | (2S)-2,6-diamino-N-(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl)hexanamide | Drug Info |
| MMP2 --- MMP9 | N-hydroxy-3-(N-(4-(p-tolyloxy)phenyl)methan-15-ylsulfonamido)propanamide | Drug Info |
| MMP2 --- MMP9 | 5-(biphenyl-4-yl)-5-(4-(4-nitrophenyl)piperazin-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| MMP2 --- MMP9 | (S)-3-(N-(4-(4-fluorobenzyloxy)phenyl)methan-8-ylsulfonamido)-N,2-dihydroxypropanamide | Drug Info |
| MMP2 --- MMP9 | 5-(4-(Thiophene-2-carbonyl)piperazin-1-yl)-5-(4-phenoxyphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| MMP2 --- MMP9 | (S)-2-(3-chlorophenylamino)-N-hydroxy-3-(N-(4-(p-tolyloxy)phenyl)methan-2-ylsulfonamido)propanamide | Drug Info |
| MMP2 --- MMP9 | 5-(4-Phenoxyphenyl)-5-(4-(6-chloropyridine-3-carbonyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| MMP2 --- MMP9 | (-)-(R)-N-(1-hydroxy-2-oxo-2,3,4,7-tetrahydro-1H-azepin-3-yl)-4-(4-(trifluoromethyl)phenoxy)benzenesulfonamide | Drug Info |
| MMP2 --- MMP9 | (R)-3-(1H-Indol-3-yl)-2-[4-(4-methoxy-phenylethynyl)-3-nitro-benzenesulfonylamino]-propionic acid | Drug Info |
| MMP2 --- MMP9 | 2-[7-(2,6-Dimethyl-pyridin-4-ylmethoxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-propionamide | Drug Info |
| MMP2 --- MMP9 | 5-(4-Phenoxyphenyl)-5-(4-(4-(methylthio)benzoyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| MMP2 --- MMP9 | N-benzyl-N-(1-hydroxy-2-oxo-1,2-dihydropyridin-3-yl)-4-phenoxybenzenesulfonamide | Drug Info |
| MMP2 --- MMP9 | (R)-3-(1H-Indol-3-yl)-2-(5-o-tolylethynyl-thiophene-2-sulfonylamino)-propionic acid | Drug Info |
| MMP2 --- MMP9 | (R)-3-(1H-Indol-3-yl)-2-[5-(4-phenoxy-phenylethynyl)-thiophene-2-sulfonylamino]-propionic acid | Drug Info |
| MMP2 --- MMP9 | (2R)-[(4-biphenylylsulfonyl) amino]-N-hydroxy-3-phenylpropionamide | Drug Info |
| MMP2 --- MMP9 | (S)-N-hydroxy-2-(3-methoxyphenylamino)-3-(N-(4-(p-tolyloxy)phenyl)methan-2-ylsulfonamido)propanamide | Drug Info |
| MMP2 --- MMP9 | 5-(4-Phenoxyphenyl)-5-(4-(quinoxaline-2-carbonyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| MMP2 --- MMP9 | N-(1-hydroxy-2-oxo-1,2-dihydropyridin-3-yl)-N-methyl-4-(4-(trifluoromethyl)phenoxy)benzenesulfonamide | Drug Info |
| MMP2 --- MMP9 | (S)-2-(4-acetylpiperazin-1-yl)-N-hydroxy-3-(N-(4-(4-(trifluoromethyl)phenoxy)phenyl)methan-2-ylsulfonamido)propanamide | Drug Info |
| MMP2 --- MMP9 | 4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(4'-fluoro-biphenyl-4-sulfonyl)-butyric acid | Drug Info |
| MMP2 --- MMP9 | 5-(4-Phenoxyphenyl)-5-(4-(3-chloro-6-fluorobenzo-[b]-thiophene-2-carbonyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6-(1H,3H,5H)-trione | Drug Info |
| MMP2 --- MMP9 | 5-(4-Phenoxyphenyl)-5-(4-(thiophene-2-carbonyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| MMP2 --- MMP9 | N-{(S)-1-hydroxycarbamoyl-2-[methanesulfonyl-(4-p-tolyloxy-phenyl)-amino]-ethyl}-isobutyramide | Drug Info |
| MMP2 --- MMP9 | (S)-N,2-dihydroxy-3-(N-(4-(2-p-tolylethynyl)phenyl)methan-8-ylsulfonamido)propanamide | Drug Info |
| MMP2 --- MMP9 | 5-(4-Phenoxyphenyl)-5-(4-(4-methylbenzoyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| MMP2 --- MMP9 | 5-(4-Phenoxyphenyl)-5-(cyclopropylmethyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| MMP2 --- MMP9 | N-(1-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-3-(4-(4-(trifluoromethoxy)phenoxy)phenylsulfonyl)propan-2-yl)-N-hydroxyformamide | Drug Info |
| MMP2 --- MMP9 | (R)-3-Methyl-2-[4-(2-phenyl-2H-tetrazol-5-yl)-benzenesulfonylamino]-butyric acid | Drug Info |
| MMP2 --- MMP9 | (S)-2-(4-(4-chlorophenyl)piperazin-1-yl)-N-hydroxy-3-(N-(4-(4-(trifluoromethyl)phenoxy)phenyl)methan-2-ylsulfonamido)propanamide | Drug Info |
| MMP2 --- MMP9 | 5-(4-Phenoxyphenyl)-5-(4-(4-(trifluoromethoxy)benzoyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
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