Drug Information

Drug General Information
Drug ID
DXY4HQ
Drug Name
{2-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-oxo-ethyl}-carbamic acid tert-butyl ester
Synonyms
CHEMBL323298
Indication Discovery agent Investigative [1587926]
Formula
C26H30ClN3O3
Canonical SMILES
CC(C)(C)OC(=O)NCC(=O)N1CCC(=C2c3ccc(Cl)cc3CCc4cccnc24)CC1
InChI
InChI=1S/C26H30ClN3O3/c1-26(2,3)33-25(32)29-16-22(31)30-13-10-17(11-14-30)23-21-9-8-20(27)15-19(21)7-6-18-5-4-12-28-24(18)23/h4-5,8-9,12,15H,6-7,10-11,13-14,16H2,1-3H3,(H,29,32)
InChIKey
GTXYUTCMCYHTIT-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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