Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXX3XI
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| Drug Name |
4-(Benzothiazol-6-ylamino)-6-(benzyl-isopropyl-amino)-[1,3,5]triazin-2-ol
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| Synonyms |
CHEMBL176019
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C20H20N6OS
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| Canonical SMILES |
CC(C)N(Cc1ccccc1)c2nc(O)nc(Nc3ccc4ncsc4c3)n2
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| InChI |
InChI=1S/C20H20N6OS/c1-13(2)26(11-14-6-4-3-5-7-14)19-23-18(24-20(27)25-19)22-15-8-9-16-17(10-15)28-12-21-16/h3-10,12-13H,11H2,1-2H3,(H2,22,23,24,25,27)
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| InChIKey |
AODUHZPEXFCKHF-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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