Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXS1LK
|
||||
| Drug Name |
2-Chloro-5-[(R)-2-cyano-2-((S)-2-phenylamino-3-m-tolyl-propionylamino)-ethoxymethyl]-benzoic acid
|
||||
| Synonyms |
CHEMBL334879
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H26ClN3O4
|
||||
| Canonical SMILES |
Cc1cccc(C[C@H](Nc2ccccc2)C(=O)N[C@@H](COCc3ccc(Cl)c(c3)C(=O)O)C#N)c1
|
||||
| InChI |
InChI=1S/C27H26ClN3O4/c1-18-6-5-7-19(12-18)14-25(30-21-8-3-2-4-9-21)26(32)31-22(15-29)17-35-16-20-10-11-24(28)23(13-20)27(33)34/h2-13,22,25,30H,14,16-17H2,1H3,(H,31,32)(H,33,34)/t22-,25+/m1/s1
|
||||
| InChIKey |
IHOKXHNBNUTHMF-RDGATRHJSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.