Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXR4XW
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| Drug Name |
[(S)-1-((5S,6S)-7-Oxo-4-oxa-1-aza-bicyclo[3.2.0]hept-6-ylcarbamoyl)-2-phenyl-propyl]-carbamic acid benzyl ester
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| Synonyms |
CHEMBL115734
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C22H23N3O5
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| Canonical SMILES |
O=C(N[C@@H](Cc1ccccc1)C(=O)N[C@H]2[C@@H]3OCCN3C2=O)OCc4ccccc4
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| InChI |
InChI=1S/C22H23N3O5/c26-19(24-18-20(27)25-11-12-29-21(18)25)17(13-15-7-3-1-4-8-15)23-22(28)30-14-16-9-5-2-6-10-16/h1-10,17-18,21H,11-14H2,(H,23,28)(H,24,26)/t17-,18+,21-/m0/s1
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| InChIKey |
VYRSXJDNPISAMG-UEXGIBASSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | RANKL/RANK Signaling Pathway | ||||
| Osteoclast Signaling | |||||
| References | |||||
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