Drug Information

Drug General Information
Drug ID
DXR1RC
Drug Name
4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-(5-oxo-hexanoyl)-piperazine-2-carboxylic acid (pyridin-3-ylmethyl)-amide
Synonyms
CHEMBL381736
Indication Discovery agent Investigative [1587926]
Formula
C31H33BrClN5O3
Canonical SMILES
CC(=O)CCCC(=O)N1CCN(CC1C(=O)NCc2cccnc2)C3c4ccc(Cl)cc4CCc5cc(Br)cnc35
InChI
InChI=1S/C31H33BrClN5O3/c1-20(39)4-2-6-28(40)38-13-12-37(19-27(38)31(41)36-17-21-5-3-11-34-16-21)30-26-10-9-25(33)15-22(26)7-8-23-14-24(32)18-35-29(23)30/h3,5,9-11,14-16,18,27,30H,2,4,6-8,12-13,17,19H2,1H3,(H,36,41)
InChIKey
SWZGYZRZEHXDAJ-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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