Drug Information

Drug General Information
Drug ID
DXR0GW
Drug Name
(10R,13S)-10,13-Dimethyl-4-trifluoromethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione
Synonyms
CHEMBL104218
Indication Discovery agent Investigative [1587926]
Formula
C20H25F3O2
Canonical SMILES
C[C@]12CCC3C(CCC4=C(C(=O)CC[C@]34C)C(F)(F)F)C1CCC2=O
InChI
InChI=1S/C20H25F3O2/c1-18-10-8-15(24)17(20(21,22)23)14(18)4-3-11-12-5-6-16(25)19(12,2)9-7-13(11)18/h11-13H,3-10H2,1-2H3/t11?,12?,13?,18-,19+/m1/s1
InChIKey
OMHOOFKINHBDCB-FWMAMRLESA-N
Target and Pathway
Target(s) 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Target Info [1587926]
3-oxo-5-alpha-steroid 4-dehydrogenase 2 Target Info [1587926]
BioCyc Pathway Superpathway of steroid hormone biosynthesis
Allopregnanolone biosynthesis
Androgen biosynthesisPWY-7305:Superpathway of steroid hormone biosynthesis
Androgen biosynthesis
KEGG Pathway Steroid hormone biosynthesishsa00140:Steroid hormone biosynthesis
Prostate cancer
NetPath Pathway IL2 Signaling Pathway
PathWhiz Pathway Androgen and Estrogen Metabolism
Reactome Androgen biosynthesisR-HSA-193048:Androgen biosynthesis
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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