Drug Information

Drug General Information
Drug ID
DXOH4G
Drug Name
4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1,2-dicarboxylic acid 1-cyclohexylamide 2-[(3-imidazol-1-yl-propyl)-amide] 1-cycloheptylamide 2-[(pyridin-3-ylmethyl)-amide]
Synonyms
CHEMBL372350
Indication Discovery agent Investigative [1587926]
Formula
C33H38BrClN6O2
Canonical SMILES
Clc1ccc2C(N3CCN(C(C3)C(=O)NCc4cccnc4)C(=O)NC5CCCCCC5)c6ncc(Br)cc6CCc2c1
InChI
InChI=1S/C33H38BrClN6O2/c34-25-16-24-10-9-23-17-26(35)11-12-28(23)31(30(24)37-20-25)40-14-15-41(33(43)39-27-7-3-1-2-4-8-27)29(21-40)32(42)38-19-22-6-5-13-36-18-22/h5-6,11-13,16-18,20,27,29,31H,1-4,7-10,14-15,19,21H2,(H,38,42)(H,39,43)
InChIKey
YZPIHUPBGVJAAS-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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