Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXN5ZK
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| Drug Name |
6-(biphenyl-4-ylmethyl)-N4-(3-bromophenyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
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| Synonyms |
CHEMBL1956887
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H20BrN5
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| Canonical SMILES |
Nc1nc(Nc2cccc(Br)c2)c3cc(Cc4ccc(cc4)c5ccccc5)[nH]c3n1
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| InChI |
InChI=1S/C25H20BrN5/c26-19-7-4-8-20(14-19)28-23-22-15-21(29-24(22)31-25(27)30-23)13-16-9-11-18(12-10-16)17-5-2-1-3-6-17/h1-12,14-15H,13H2,(H4,27,28,29,30,31)
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| InChIKey |
OBTGJXIDKZVSAG-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Epidermal growth factor receptor III | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathway | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY network | |||||
| References | |||||
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