Drug Information
| Drug General Information | |||||
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| Drug ID |
DXN0LT
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| Drug Name |
(R)-1-(5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl)-3,3-dimethylbutan-2-yl(S)-1,2-dioxo-1-((S)-2-oxopiperidin-3-ylamino)heptan-3-ylcarbamate
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| Synonyms |
CHEMBL1087934
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H36FN5O6
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| Canonical SMILES |
CCCC[C@H](NC(=O)O[C@H](Cc1oc(nn1)c2ccc(F)cc2)C(C)(C)C)C(=O)C(=O)N[C@H]3CCCNC3=O
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| InChI |
InChI=1S/C27H36FN5O6/c1-5-6-8-18(22(34)24(36)30-19-9-7-14-29-23(19)35)31-26(37)38-20(27(2,3)4)15-21-32-33-25(39-21)16-10-12-17(28)13-11-16/h10-13,18-20H,5-9,14-15H2,1-4H3,(H,29,35)(H,30,36)(H,31,37)/t18-,19-,20+/m0/s1
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| InChIKey |
AQMZQDJVQGMOQG-SLFFLAALSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | RANKL/RANK Signaling Pathway | ||||
| Osteoclast Signaling | |||||
| References | |||||
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